Cancer Prevention: What's on the Horizon?

As early as 2006, we were seeing news articles about the possibility of a vaccine coming to market to fight cervical cancer. At that time, the HPV vaccine was in the final stages of research, and was under review by the FDA. In the summer of that year, the vaccine was approved for girls and young women, and was later approved for males as well. It is now considered a vital tool in the prevention of cervical cancer in men and women, and is as close to being a "cure" as we have seen to date.

Just like those conducted on the HPV vaccine, there are hundreds more clinical research trials being done every day that are investigating the effectiveness of newly developed drugs and procedures. Clinical trials are a vital key to removing the word cancer from "household word" status.

Cancer research trials are conducted for many reasons. Some are simply focused on finding a "cure". Sometimes, these lead to discoveries that were unexpected - such as a medication that was being used to treat one kind of cancer that is then found to be effective on another type, or even another disease altogether. In other studies, researchers may be trying to discover ways to manage symptoms or after-effects of treatment such as "chemo-brain" and post-radiation nerve damage. Trials are also conducted that study the psychological impact of medical treatments and offer new "best practices" for doctors in order to prevent patients from suffering emotional distress during their treatment and recovery.

For a patient, the decision to participating in a clinical trial can be a difficult one to make. Many trials are "double-blind", meaning that the doctor and the patient don't know if the syringe or i.v. of fluid being administered is actually a newly created medication, or a placebo. Entering into that kind of study means placing faith in the importance of the study, not necessarily in any improvement that might be seen by the patient themselves.

There are many benefits to participating in a clinical trial. They offer a level of care that may be a step up from the standard if the treatment you are receiving is found to be effective. Participation can empower a patient and allow them take a lead role in their treatment plan. The psychological effect of this can be beneficial to many patients - feeling "helpless" is a common complaint of cancer patients who are undergoing cancer treatment and request counseling support. Finally, participation in clinical trials allows patients to become part of the important work being done to improve cancer treatment and find cures on a national and global scale. The ongoing legacy of cancer trial participants is significant.

Of course, there can be drawbacks to participation, and patients have to discuss them with their physician as well. There could be side-effects that doctors are not yet aware of. Even if the new treatment has benefits, it may not work on every patient. Health insurance does not always cover all the costs of a research study. New treatments may simply not be any better than the standard of care, which would mean that money spent and side-effects endured may be of no benefit to the individual patient. That's where the ongoing legacy comes in... the more people that are involved in trials, the more quickly the most effective treatment options and cures will be discovered.

More information on clinical trials being conducted in Northwest Arkansas is available on the Highlands Oncology Group website. Their research staff is on the fore-front of the cancer fight and can provide additional information for patients interested in looking at all their treatment options.